Insights

NICE recommends cemiplimab for recurrent or metastatic cervical cancer

Cemiplimab is now a new NHS option for recurrent or metastatic cervical cancer.

NICE has published final draft guidance recommending cemiplimab (Libtayo, Regeneron) for adults whose cancer has worsened during or after platinum-based chemotherapy, and who have not previously had immunotherapy.

Key points

  • Around 90 adults a year are expected to be eligible.

  • NICE said the treatment can prolong the time before disease progression and improve overall survival versus standard chemotherapy.

  • Trial data from EMPOWER Cervical-1 showed average survival of 11.7 months with cemiplimab, compared with 8.5 months with single-agent chemotherapy.

  • At 24 months, more than twice as many patients treated with cemiplimab were still alive.

  • The treatment will be available immediately via the Cancer Drugs Fund before moving to routine NHS commissioning 90 days after final guidance is published.

Read more at https://www.nice.org.uk/news/articles/new-treatment-option-recommended-for-recurrent-or-metastatic-cervical-cancer

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